Recent research (Nakagawa et al. 2017) indicates that immune treatment can be effective for cases of recurrent miscarriage.

Miscarriage, the loss of a pregnancy before a viable gestation, affects 1 in 6 couples. However, Recurrent pregnancy loss (RPL), where two or more miscarriages have occurred, affects up to 1.9% of couples. For up to 50% of these couples the reason behind this condition cannot be identified. Much recent research has strived to understand this, with immune treatment.

Type 1 T helper (Th1) and Type 2 (Th2) cells have important functions in immune responses and there is a general agreement that pregnancy is associated with Th2 cell dominance.

Recent research (Nakagawa et al. 2017) indicates that immunosuppressive treatment can be effective in cases of recurrent miscarriage, with elevated Th1/Th2 cell ratio after achieving pregnancy.

Read the full report here.

Nakagawa, K. Kuroda, K., Sugiyama,R and Yamaguchi, K., (2017) ‘After 12 consecutive miscarriages, a patient received immunosuppressive treatment and delivered an intact baby’, Journal: Reproductive Medicine and Biology, Vol: 16, p. 297 – 30.