{"id":1215,"date":"2019-11-27T11:22:06","date_gmt":"2019-11-27T09:22:06","guid":{"rendered":"http:\/\/lifeclinic.gr\/services\/assisted-reproduction\/health-check\/dna-fragmentation-fish-fragmentation\/"},"modified":"2023-03-16T13:07:43","modified_gmt":"2023-03-16T11:07:43","slug":"dna-fragmentation-fish-fragmentation","status":"publish","type":"page","link":"https:\/\/lifeclinic.gr\/en\/services\/assisted-reproduction\/genetic-fertility-testing\/dna-fragmentation-fish-fragmentation\/","title":{"rendered":"Sperm DNA fragmentation"},"content":{"rendered":"<div class=\"wpb-content-wrapper\"><p>[vc_row][vc_column][vc_row_inner][vc_column_inner][tm_heading tag=&#8221;h1&#8243; custom_google_font=&#8221;&#8221; text=&#8221;Sperm DNA fragmentation (SDF)&#8221;][tm_spacer size=&#8221;lg:30&#8243;][\/vc_column_inner][\/vc_row_inner][\/vc_column][\/vc_row][vc_row][vc_column width=&#8221;2\/3&#8243;][vc_column_text]In 1980, the first SDF test, the Sperm Chromatin Structure Assay (<a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC5643675\/\">SCSA<\/a>)\u00a0 was introduced. It \u201cmeasures the susceptibility of DNA to denaturation, which occurs more commonly in fragmented DNA\u201d, or in other words it is able to estimate\u00a0the proportion of healthy spermatozoa in relation to those that have altered DNA inside them.<\/p>\n<p>A sperm with fragmented DNA will lead to a pregnancy that has high chances for miscarriage and if not, with a malformed fetus that cannot survive.<\/p>\n<p>This test is mainly used as a predictor and can sometimes justify unexplained infertility or predict a poor assisted reproductive outcome.<\/p>\n<p><strong>Impact on fertility<\/strong><\/p>\n<p>Both elevated sperm DNA fragmentation and poor sperm viability are linked to male infertility.[\/vc_column_text][tm_spacer size=&#8221;lg:20&#8243;][\/vc_column][vc_column width=&#8221;1\/3&#8243;][tm_image image=&#8221;15810&#8243;][tm_spacer size=&#8221;lg:20&#8243;][\/vc_column][\/vc_row]<\/p>\n<\/div>","protected":false},"excerpt":{"rendered":"<p>[vc_row][vc_column][vc_row_inner][vc_column_inner][tm_heading tag=&#8221;h1&#8243; custom_google_font=&#8221;&#8221; text=&#8221;Sperm DNA fragmentation (SDF)&#8221;][tm_spacer size=&#8221;lg:30&#8243;][\/vc_column_inner][\/vc_row_inner][\/vc_column][\/vc_row][vc_row][vc_column width=&#8221;2\/3&#8243;][vc_column_text]In 1980, the first SDF test, the Sperm Chromatin Structure Assay (SCSA)\u00a0 was introduced. It \u201cmeasures the susceptibility of DNA to denaturation, which occurs more commonly in fragmented DNA\u201d, or in other words it is able to estimate\u00a0the proportion of healthy spermatozoa in relation to those that have altered DNA inside them. A sperm with fragmented DNA will lead to a pregnancy that has high chances for miscarriage and if not, with a malformed fetus that cannot survive. This test is mainly used as a predictor and can sometimes justify unexplained infertility or predict a poor assisted reproductive outcome. Impact on fertility Both elevated sperm DNA fragmentation and poor sperm viability are linked to male infertility.[\/vc_column_text][tm_spacer size=&#8221;lg:20&#8243;][\/vc_column][vc_column width=&#8221;1\/3&#8243;][tm_image image=&#8221;15810&#8243;][tm_spacer size=&#8221;lg:20&#8243;][\/vc_column][\/vc_row]<\/p>\n","protected":false},"author":4,"featured_media":0,"parent":1212,"menu_order":102,"comment_status":"closed","ping_status":"closed","template":"","meta":{"footnotes":""},"class_list":["post-1215","page","type-page","status-publish","hentry"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.2 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Sperm DNA fragmentation - LifeClinic<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/lifeclinic.gr\/en\/services\/assisted-reproduction\/genetic-fertility-testing\/dna-fragmentation-fish-fragmentation\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Sperm DNA fragmentation - LifeClinic\" \/>\n<meta property=\"og:description\" content=\"[vc_row][vc_column][vc_row_inner][vc_column_inner][tm_heading tag=&#8221;h1&#8243; custom_google_font=&#8221;&#8221; text=&#8221;Sperm DNA fragmentation (SDF)&#8221;][tm_spacer size=&#8221;lg:30&#8243;][\/vc_column_inner][\/vc_row_inner][\/vc_column][\/vc_row][vc_row][vc_column width=&#8221;2\/3&#8243;][vc_column_text]In 1980, the first SDF test, the Sperm Chromatin Structure Assay (SCSA)\u00a0 was introduced. It \u201cmeasures the susceptibility of DNA to denaturation, which occurs more commonly in fragmented DNA\u201d, or in other words it is able to estimate\u00a0the proportion of healthy spermatozoa in relation to those that have altered DNA inside them. A sperm with fragmented DNA will lead to a pregnancy that has high chances for miscarriage and if not, with a malformed fetus that cannot survive. This test is mainly used as a predictor and can sometimes justify unexplained infertility or predict a poor assisted reproductive outcome. Impact on fertility Both elevated sperm DNA fragmentation and poor sperm viability are linked to male infertility.[\/vc_column_text][tm_spacer size=&#8221;lg:20&#8243;][\/vc_column][vc_column width=&#8221;1\/3&#8243;][tm_image image=&#8221;15810&#8243;][tm_spacer size=&#8221;lg:20&#8243;][\/vc_column][\/vc_row]\" \/>\n<meta property=\"og:url\" content=\"https:\/\/lifeclinic.gr\/en\/services\/assisted-reproduction\/genetic-fertility-testing\/dna-fragmentation-fish-fragmentation\/\" \/>\n<meta property=\"og:site_name\" content=\"LifeClinic\" \/>\n<meta property=\"article:publisher\" content=\"https:\/\/www.facebook.com\/lifeclinicathens\/\" \/>\n<meta property=\"article:modified_time\" content=\"2023-03-16T11:07:43+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/i0.wp.com\/lifeclinic.gr\/wp-content\/uploads\/2019\/11\/LOGO_HIGH_RESOL.jpg?fit=1296%2C1920&ssl=1\" \/>\n\t<meta property=\"og:image:width\" content=\"1296\" \/>\n\t<meta property=\"og:image:height\" content=\"1920\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/jpeg\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data1\" content=\"1 minute\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"WebPage\",\"@id\":\"https:\/\/lifeclinic.gr\/en\/services\/assisted-reproduction\/genetic-fertility-testing\/dna-fragmentation-fish-fragmentation\/\",\"url\":\"https:\/\/lifeclinic.gr\/en\/services\/assisted-reproduction\/genetic-fertility-testing\/dna-fragmentation-fish-fragmentation\/\",\"name\":\"Sperm DNA fragmentation - LifeClinic\",\"isPartOf\":{\"@id\":\"https:\/\/lifeclinic.gr\/#website\"},\"datePublished\":\"2019-11-27T09:22:06+00:00\",\"dateModified\":\"2023-03-16T11:07:43+00:00\",\"breadcrumb\":{\"@id\":\"https:\/\/lifeclinic.gr\/en\/services\/assisted-reproduction\/genetic-fertility-testing\/dna-fragmentation-fish-fragmentation\/#breadcrumb\"},\"inLanguage\":\"en-US\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\/\/lifeclinic.gr\/en\/services\/assisted-reproduction\/genetic-fertility-testing\/dna-fragmentation-fish-fragmentation\/\"]}]},{\"@type\":\"BreadcrumbList\",\"@id\":\"https:\/\/lifeclinic.gr\/en\/services\/assisted-reproduction\/genetic-fertility-testing\/dna-fragmentation-fish-fragmentation\/#breadcrumb\",\"itemListElement\":[{\"@type\":\"ListItem\",\"position\":1,\"name\":\"Home\",\"item\":\"https:\/\/lifeclinic.gr\/en\/\"},{\"@type\":\"ListItem\",\"position\":2,\"name\":\"Services\",\"item\":\"https:\/\/lifeclinic.gr\/ypiresies\/\"},{\"@type\":\"ListItem\",\"position\":3,\"name\":\"Assisted reproduction\",\"item\":\"https:\/\/lifeclinic.gr\/en\/services\/assisted-reproduction\/\"},{\"@type\":\"ListItem\",\"position\":4,\"name\":\"Genetic and Fertility Testing\",\"item\":\"https:\/\/lifeclinic.gr\/en\/services\/assisted-reproduction\/genetic-fertility-testing\/\"},{\"@type\":\"ListItem\",\"position\":5,\"name\":\"Sperm DNA fragmentation\"}]},{\"@type\":\"WebSite\",\"@id\":\"https:\/\/lifeclinic.gr\/#website\",\"url\":\"https:\/\/lifeclinic.gr\/\",\"name\":\"Life Clinic\",\"description\":\"Centre for Assisted Reproduction &amp; Gynaecology, Athens, Greece\",\"publisher\":{\"@id\":\"https:\/\/lifeclinic.gr\/#organization\"},\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"https:\/\/lifeclinic.gr\/?s={search_term_string}\"},\"query-input\":{\"@type\":\"PropertyValueSpecification\",\"valueRequired\":true,\"valueName\":\"search_term_string\"}}],\"inLanguage\":\"en-US\"},{\"@type\":\"Organization\",\"@id\":\"https:\/\/lifeclinic.gr\/#organization\",\"name\":\"lifeclinic\",\"url\":\"https:\/\/lifeclinic.gr\/\",\"logo\":{\"@type\":\"ImageObject\",\"inLanguage\":\"en-US\",\"@id\":\"https:\/\/lifeclinic.gr\/#\/schema\/logo\/image\/\",\"url\":\"https:\/\/lifeclinic.gr\/wp-content\/uploads\/2019\/11\/logo_LC-stacked.png\",\"contentUrl\":\"https:\/\/lifeclinic.gr\/wp-content\/uploads\/2019\/11\/logo_LC-stacked.png\",\"width\":204,\"height\":300,\"caption\":\"lifeclinic\"},\"image\":{\"@id\":\"https:\/\/lifeclinic.gr\/#\/schema\/logo\/image\/\"},\"sameAs\":[\"https:\/\/www.facebook.com\/lifeclinicathens\/\"]}]}<\/script>\n<!-- \/ Yoast SEO plugin. -->","yoast_head_json":{"title":"Sperm DNA fragmentation - LifeClinic","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/lifeclinic.gr\/en\/services\/assisted-reproduction\/genetic-fertility-testing\/dna-fragmentation-fish-fragmentation\/","og_locale":"en_US","og_type":"article","og_title":"Sperm DNA fragmentation - LifeClinic","og_description":"[vc_row][vc_column][vc_row_inner][vc_column_inner][tm_heading tag=&#8221;h1&#8243; custom_google_font=&#8221;&#8221; text=&#8221;Sperm DNA fragmentation (SDF)&#8221;][tm_spacer size=&#8221;lg:30&#8243;][\/vc_column_inner][\/vc_row_inner][\/vc_column][\/vc_row][vc_row][vc_column width=&#8221;2\/3&#8243;][vc_column_text]In 1980, the first SDF test, the Sperm Chromatin Structure Assay (SCSA)\u00a0 was introduced. It \u201cmeasures the susceptibility of DNA to denaturation, which occurs more commonly in fragmented DNA\u201d, or in other words it is able to estimate\u00a0the proportion of healthy spermatozoa in relation to those that have altered DNA inside them. A sperm with fragmented DNA will lead to a pregnancy that has high chances for miscarriage and if not, with a malformed fetus that cannot survive. This test is mainly used as a predictor and can sometimes justify unexplained infertility or predict a poor assisted reproductive outcome. Impact on fertility Both elevated sperm DNA fragmentation and poor sperm viability are linked to male infertility.[\/vc_column_text][tm_spacer size=&#8221;lg:20&#8243;][\/vc_column][vc_column width=&#8221;1\/3&#8243;][tm_image image=&#8221;15810&#8243;][tm_spacer size=&#8221;lg:20&#8243;][\/vc_column][\/vc_row]","og_url":"https:\/\/lifeclinic.gr\/en\/services\/assisted-reproduction\/genetic-fertility-testing\/dna-fragmentation-fish-fragmentation\/","og_site_name":"LifeClinic","article_publisher":"https:\/\/www.facebook.com\/lifeclinicathens\/","article_modified_time":"2023-03-16T11:07:43+00:00","og_image":[{"width":1296,"height":1920,"url":"https:\/\/i0.wp.com\/lifeclinic.gr\/wp-content\/uploads\/2019\/11\/LOGO_HIGH_RESOL.jpg?fit=1296%2C1920&ssl=1","type":"image\/jpeg"}],"twitter_card":"summary_large_image","twitter_misc":{"Est. reading time":"1 minute"},"schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"WebPage","@id":"https:\/\/lifeclinic.gr\/en\/services\/assisted-reproduction\/genetic-fertility-testing\/dna-fragmentation-fish-fragmentation\/","url":"https:\/\/lifeclinic.gr\/en\/services\/assisted-reproduction\/genetic-fertility-testing\/dna-fragmentation-fish-fragmentation\/","name":"Sperm DNA fragmentation - LifeClinic","isPartOf":{"@id":"https:\/\/lifeclinic.gr\/#website"},"datePublished":"2019-11-27T09:22:06+00:00","dateModified":"2023-03-16T11:07:43+00:00","breadcrumb":{"@id":"https:\/\/lifeclinic.gr\/en\/services\/assisted-reproduction\/genetic-fertility-testing\/dna-fragmentation-fish-fragmentation\/#breadcrumb"},"inLanguage":"en-US","potentialAction":[{"@type":"ReadAction","target":["https:\/\/lifeclinic.gr\/en\/services\/assisted-reproduction\/genetic-fertility-testing\/dna-fragmentation-fish-fragmentation\/"]}]},{"@type":"BreadcrumbList","@id":"https:\/\/lifeclinic.gr\/en\/services\/assisted-reproduction\/genetic-fertility-testing\/dna-fragmentation-fish-fragmentation\/#breadcrumb","itemListElement":[{"@type":"ListItem","position":1,"name":"Home","item":"https:\/\/lifeclinic.gr\/en\/"},{"@type":"ListItem","position":2,"name":"Services","item":"https:\/\/lifeclinic.gr\/ypiresies\/"},{"@type":"ListItem","position":3,"name":"Assisted reproduction","item":"https:\/\/lifeclinic.gr\/en\/services\/assisted-reproduction\/"},{"@type":"ListItem","position":4,"name":"Genetic and Fertility Testing","item":"https:\/\/lifeclinic.gr\/en\/services\/assisted-reproduction\/genetic-fertility-testing\/"},{"@type":"ListItem","position":5,"name":"Sperm DNA fragmentation"}]},{"@type":"WebSite","@id":"https:\/\/lifeclinic.gr\/#website","url":"https:\/\/lifeclinic.gr\/","name":"Life Clinic","description":"Centre for Assisted Reproduction &amp; Gynaecology, Athens, Greece","publisher":{"@id":"https:\/\/lifeclinic.gr\/#organization"},"potentialAction":[{"@type":"SearchAction","target":{"@type":"EntryPoint","urlTemplate":"https:\/\/lifeclinic.gr\/?s={search_term_string}"},"query-input":{"@type":"PropertyValueSpecification","valueRequired":true,"valueName":"search_term_string"}}],"inLanguage":"en-US"},{"@type":"Organization","@id":"https:\/\/lifeclinic.gr\/#organization","name":"lifeclinic","url":"https:\/\/lifeclinic.gr\/","logo":{"@type":"ImageObject","inLanguage":"en-US","@id":"https:\/\/lifeclinic.gr\/#\/schema\/logo\/image\/","url":"https:\/\/lifeclinic.gr\/wp-content\/uploads\/2019\/11\/logo_LC-stacked.png","contentUrl":"https:\/\/lifeclinic.gr\/wp-content\/uploads\/2019\/11\/logo_LC-stacked.png","width":204,"height":300,"caption":"lifeclinic"},"image":{"@id":"https:\/\/lifeclinic.gr\/#\/schema\/logo\/image\/"},"sameAs":["https:\/\/www.facebook.com\/lifeclinicathens\/"]}]}},"_links":{"self":[{"href":"https:\/\/lifeclinic.gr\/en\/wp-json\/wp\/v2\/pages\/1215","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeclinic.gr\/en\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/lifeclinic.gr\/en\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/lifeclinic.gr\/en\/wp-json\/wp\/v2\/users\/4"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeclinic.gr\/en\/wp-json\/wp\/v2\/comments?post=1215"}],"version-history":[{"count":0,"href":"https:\/\/lifeclinic.gr\/en\/wp-json\/wp\/v2\/pages\/1215\/revisions"}],"up":[{"embeddable":true,"href":"https:\/\/lifeclinic.gr\/en\/wp-json\/wp\/v2\/pages\/1212"}],"wp:attachment":[{"href":"https:\/\/lifeclinic.gr\/en\/wp-json\/wp\/v2\/media?parent=1215"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}