{"id":1211,"date":"2019-11-27T11:17:05","date_gmt":"2019-11-27T09:17:05","guid":{"rendered":"http:\/\/lifeclinic.gr\/services\/assisted-reproduction\/cryopreservation\/fetal-cryopreservation\/"},"modified":"2022-12-06T20:03:27","modified_gmt":"2022-12-06T18:03:27","slug":"embryo-cryopreservation","status":"publish","type":"page","link":"https:\/\/lifeclinic.gr\/en\/services\/assisted-reproduction\/cryopreservation\/embryo-cryopreservation\/","title":{"rendered":"Embryo cryopreservation"},"content":{"rendered":"

[vc_row][vc_column][tm_heading tag=”h1″ custom_google_font=”” text_color=”custom” custom_text_color=”#ff6400″ text=”What is embryo cryopreservation?” font_size=”lg:36″][tm_spacer size=”lg:25″][vc_row_inner][vc_column_inner width=”1\/2″][vc_column_text]Embryo cryopreservation<\/em>\u00a0or\u00a0embryo freezing<\/em> is the process of freezing and storing the embryos produced, from fresh cycle IVF treatment, for future use. It is the most effective technique for fertility preservation in women and is often included in part of IVF programmes to ensure the future use of unused embryos. Often fertility treatments, such as IVF, ICSI and egg donation, generate surplus healthy embryos. In around 50% of cases these embryos are of good enough quality to be frozen and stored for future use. Embryo freezing, therefore, offers greater flexibility to couples in their family planning and can be used effectively to reduce the number of multiple births. If after family building, there are unwanted and remaining embryos they can be optionally donated to other infertile couples.[\/vc_column_text][tm_spacer size=”lg:25″][\/vc_column_inner][vc_column_inner width=”1\/2″][tm_image image=”14175″][tm_spacer size=”lg:35″][vc_column_text]<\/p>\n

Embryo freezing maximises the use of embryos produced from a fresh cycle and increases the chances to conceive from the same batch of embryos. The use of frozen-thawed embryos is much less invasive procedure for the woman than undergoing a fresh IVF cycle.<\/p><\/blockquote>\n

[\/vc_column_text][tm_spacer size=”lg:35″][\/vc_column_inner][\/vc_row_inner][tm_spacer size=”lg:35″][tm_spacer size=”lg:35″][tm_heading tag=”h2″ custom_google_font=”” text=”How does cryopreservation work?” font_size=”lg:30″][tm_spacer size=”lg:25″][\/vc_column][\/vc_row][vc_row][vc_column width=”1\/2″][vc_column_text]The process involves\u00a0oocyte retrieval\u00a0from the woman and subsequent\u00a0in vitro fertilization\u00a0with her partner’s or donor sperm. The embryos are then exposed to\u00a0cryoprotectants and are carefully cooled under controlled conditions and then stored, immersed in liquid nitrogen, at very low temperatures (-196\u00baC) for long-term storage. When they are desired for use, the embryos are thawed and arrangements are made for implantation.<\/p>\n

Once frozen, embryos can be stored in this way for many years before being thawed and used in treatment. Pregnancies have been reported from frozen-thawed embryos stored for more than 30 years (see our blog – ‘Healthy twins born from 30 year old frozen embryos’<\/a>). The risk of birth defects is not increased as a result of embryo freezing.<\/p>\n

Vitrification is the most common method used for the embryo freezing, widely considered as the best method for this purpose including and the egg freezing. At Life Clinic, paying attention to every detail that can contribute to success, we are only using the best freezing kits (the Kitazato kit) <\/em>on the market. Kitazato<\/em>\u00a0is recognized as one of the pioneering brands in driving and improving vitrification.[\/vc_column_text][tm_spacer size=”lg:25″][\/vc_column][vc_column width=”1\/2″][tm_image image=”14205″][tm_spacer size=”lg:25″][\/vc_column][\/vc_row][vc_row][vc_column][tm_spacer size=”lg:40″][vc_text_separator title=”Further reading on embryo cryopreservation” i_icon_fontawesome=”fas fa-wind” i_color=”custom” add_icon=”true” i_custom_color=”#ff6400″][tm_spacer size=”lg:40″][\/vc_column][\/vc_row][vc_row][vc_column][vc_column_text]For a more in-depth review of Embryo Cryopreservation and its implications in fertility medicine, please refer to the following journal articles.[\/vc_column_text][tm_spacer size=”lg:40″][\/vc_column][\/vc_row][vc_row][vc_column width=”1\/3″][vc_cta h2=””]\"Embryo<\/p>\n

Yen and Jaffe’s Reproductive Endocrinology (2019)<\/strong><\/p>\n

Embryo cryopreservation involves many of the steps of in vitro fertilization, including stimulation of multiple follicles with FSH, prevention of premature LH surges with a GnRH analogue, triggering of the process of ovulation, retrieval of oocytes, fertilization with sperm, and cryopreservation of embryos.<\/p>\n

Read the article here<\/a><\/p>\n

From:\u00a0Yen and Jaffe’s Reproductive Endocrinology (8th ed.), 2019<\/span>[\/vc_cta][tm_spacer size=”lg:25″][\/vc_column][vc_column width=”1\/3″][vc_cta h2=””]\"\"<\/p>\n

The Future of Cryopreservation in Assisted Reproductive Technologies (2020)<\/span><\/strong><\/p>\n

In this journal article some of the latest advances, strategies, and practices in ART cycles are reviewed using elective cryopreservation of embryos, cryopreservation of oocytes, and whether these developments are likely to bring improvement to IVF outcomes.<\/p>\n

Read the article here<\/a><\/p>\n

Bosch, E., De Vos, M., Humaidan, P., Front. Endocrinol.<\/em>, 20 Feb 2020[\/vc_cta][tm_spacer size=”lg:25″][\/vc_column][vc_column width=”1\/3″][vc_cta h2=””]\"International<\/p>\n

Cryopreservation of Gametes and Embryos and Their Molecular Changes (2021)<\/span><\/strong><\/p>\n

This is a recent article that outlines cryopreservation as an ART technique. It then delves deeper into the individual procedures and methods involved including vitrification techniques and effects of cryopreservation in embryos.<\/p>\n

Read the article here<\/a><\/p>\n

Estudillo et\u00a0al.,<\/em> \u00a0International Journal of Molecular Sciences,<\/em> 2021, 22(19), 10864[\/vc_cta][tm_spacer size=”lg:25″][\/vc_column][\/vc_row]<\/p>\n<\/div>","protected":false},"excerpt":{"rendered":"

[vc_row][vc_column][tm_heading tag=”h1″ custom_google_font=”” text_color=”custom” custom_text_color=”#ff6400″ text=”What is embryo cryopreservation?” font_size=”lg:36″][tm_spacer size=”lg:25″][vc_row_inner][vc_column_inner width=”1\/2″][vc_column_text]Embryo cryopreservation\u00a0or\u00a0embryo freezing is the process of freezing and storing the embryos produced, from fresh cycle IVF treatment, for future use. It is the most effective technique for fertility preservation in women and is often included in part of IVF programmes to ensure the future use of unused embryos. Often fertility treatments, such as IVF, ICSI and egg donation, generate surplus healthy embryos. In around 50% of cases these embryos are of good enough quality to be frozen and stored for future use. Embryo freezing, therefore, offers greater flexibility to couples in their family planning and can be used effectively to reduce the number of multiple births. If after family building, there are unwanted and remaining embryos they can be optionally donated to other infertile couples.[\/vc_column_text][tm_spacer size=”lg:25″][\/vc_column_inner][vc_column_inner width=”1\/2″][tm_image image=”14175″][tm_spacer size=”lg:35″][vc_column_text] Embryo freezing maximises the use of embryos produced from a fresh cycle and increases the chances to conceive from the same batch of embryos. The use of frozen-thawed embryos is much less invasive procedure for the woman than undergoing a fresh IVF cycle. [\/vc_column_text][tm_spacer size=”lg:35″][\/vc_column_inner][\/vc_row_inner][tm_spacer size=”lg:35″][tm_spacer size=”lg:35″][tm_heading tag=”h2″ custom_google_font=”” text=”How does cryopreservation work?” font_size=”lg:30″][tm_spacer size=”lg:25″][\/vc_column][\/vc_row][vc_row][vc_column width=”1\/2″][vc_column_text]The process involves\u00a0oocyte retrieval\u00a0from the woman and subsequent\u00a0in vitro fertilization\u00a0with her partner’s or donor sperm. The embryos are then exposed to\u00a0cryoprotectants and are carefully cooled under controlled conditions and then stored, immersed in liquid nitrogen, at very low temperatures (-196\u00baC) for long-term storage. When they are desired for use, the embryos are thawed and arrangements are made for implantation. Once frozen, embryos can be stored in this way for many years before being thawed and used in treatment. Pregnancies have been reported from frozen-thawed embryos stored for more than 30 years (see our blog – ‘Healthy twins born from 30 year old frozen embryos’). The risk of birth defects is not increased as a result of embryo freezing. Vitrification is the most common method used for the embryo freezing, widely considered as the best method for this purpose including and the egg freezing. At Life Clinic, paying attention to every detail that can contribute to success, we are only using the best freezing kits (the Kitazato kit) on the market. Kitazato\u00a0is recognized as one of the pioneering brands in driving and improving vitrification.[\/vc_column_text][tm_spacer size=”lg:25″][\/vc_column][vc_column width=”1\/2″][tm_image image=”14205″][tm_spacer size=”lg:25″][\/vc_column][\/vc_row][vc_row][vc_column][tm_spacer size=”lg:40″][vc_text_separator title=”Further reading on embryo cryopreservation” i_icon_fontawesome=”fas fa-wind” i_color=”custom” add_icon=”true” i_custom_color=”#ff6400″][tm_spacer size=”lg:40″][\/vc_column][\/vc_row][vc_row][vc_column][vc_column_text]For a more in-depth review of Embryo Cryopreservation and its implications in fertility medicine, please refer to the following journal articles.[\/vc_column_text][tm_spacer size=”lg:40″][\/vc_column][\/vc_row][vc_row][vc_column width=”1\/3″][vc_cta h2=””] Yen and Jaffe’s Reproductive Endocrinology (2019) Embryo cryopreservation involves many of the steps of in vitro fertilization, including stimulation of multiple follicles with FSH, prevention of premature LH surges with a GnRH analogue, triggering of the process of ovulation, retrieval of oocytes, fertilization with sperm, and cryopreservation of embryos. Read the article here From:\u00a0Yen and Jaffe’s Reproductive Endocrinology (8th ed.), 2019[\/vc_cta][tm_spacer size=”lg:25″][\/vc_column][vc_column width=”1\/3″][vc_cta h2=””] The Future of Cryopreservation in Assisted Reproductive Technologies (2020) In this journal article some of the latest advances, strategies, and practices in ART cycles are reviewed using elective cryopreservation of embryos, cryopreservation of oocytes, and whether these developments are likely to bring improvement to IVF outcomes. Read the article here Bosch, E., De Vos, M., Humaidan, P., Front. Endocrinol., 20 Feb 2020[\/vc_cta][tm_spacer size=”lg:25″][\/vc_column][vc_column width=”1\/3″][vc_cta h2=””] Cryopreservation of Gametes and Embryos and Their Molecular Changes (2021) This is a recent article that outlines cryopreservation as an ART technique. It then delves deeper into the individual procedures and methods involved including vitrification techniques and effects of cryopreservation in embryos. Read the article here Estudillo et\u00a0al., \u00a0International Journal of Molecular Sciences, 2021, 22(19), 10864[\/vc_cta][tm_spacer size=”lg:25″][\/vc_column][\/vc_row]<\/p>\n","protected":false},"author":4,"featured_media":0,"parent":1185,"menu_order":115,"comment_status":"closed","ping_status":"closed","template":"","meta":{"footnotes":""},"class_list":["post-1211","page","type-page","status-publish","hentry"],"yoast_head":"\nEmbryo cryopreservation - LifeClinic<\/title>\n<meta name=\"description\" content=\"Embryo cryopreservation (embryo freezing) is the process of freezing & storing embryos for future use. 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